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Antonia's Hair Villi Oil.001
Antonia's Hair Villi Oil.001

Hair Villi Oil Follicle Treatment 8oz Bottle

$59.99 $29.99

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Product Description

Carcinogen Free!!!!!!

 

 

Carcinogen Free!!!!!!

Works Great with the Hair Villi Capsules and even better with the Hair Villi Kit!!!!

No Moor Polysorbate 20, Aminomethyl Propanol, Soy (A DHT attractor), Dyes/Artificial Colors!!!!!

Finally All Healthy Ingredients not just “All Natural”…. Remember Nature Makes All Natural Poisons/Toxins!!!!

Ingredients: Organic Pepermint Oil, Organic Oregano Oil, Organic Rosemary, Organic Black Castor Oil, Organic Jojoba Oil, Organic Cedarwood Oil, Organic Clary Sage Oil, Organic Spikenard Oil, Organic Grapeseed Oil, Nothing Else!!!

Peppermint Oil Promotes Hair Growth without Toxic Signs

Abstract

Peppermint (Mentha piperita) is a plant native to Europe and has been widely used as a carminative and gastric stimulant worldwide. This plant also has been used in cosmetic formulations as a fragrance component and skin conditioning agent. This study investigated the effect of peppermint oil on hair growth in C57BL/6 mice. The animals were randomized into 4 groups based on different topical applications: saline (SA), jojoba oil (JO), 3% minoxidil (MXD), and 3% peppermint oil (PEO). The hair growth effects of the 4-week topical applications were evaluated in terms of hair growth, histological analysis, enzymatic activity of alkaline phosphatase (ALP), and gene expression of insulin-like growth factor-1 (IGF-1), known bio-markers for the enhanced hair growth. Of the 4 experimental groups, PEO group showed the most prominent hair growth effects; a significant increase in dermal thickness, follicle number, and follicle depth. ALP activity and IGF-1 expression also significantly increased in PEO group. Body weight gain and food efficiency were not significantly different between groups. These results suggest that PEO induces a rapid anagen stage and could be used for a practical agent for hair growth without change of body weight gain and food efficiency.

Keywords: Alkaline phosphatase, Hair growth, Hair follicle, Insulin-like growth factor-1, Peppermint oil

INTRODUCTION

Hair loss is a distressing condition that is associated with a multitude of natural, medical, or nutritional conditions. For example, androgenetic alopecia in men, or male pattern baldness, is increasingly recognized as a physically and psychologically serious medical condition that often requires a professional care by generalist clinicians .

The only products sanctioned by the US FDA for hair loss treatment are oral finasteride (Proscar®) and topical minoxidil (Rogaine®). Minoxidil was originally created as a hypertension medication by Upjohn Pharmaceuticals . Upjohn itself has warned of possible negative side effects of the medication including increased heart rate, difficulty breathing, rapid weight gain, edema, seborrhoeic dermatitis, scalp itching, and scaling .

Traditional plant remedies have been used for centuries in the treatment for hair loss, but only a few have been scientifically evaluated . Peppermint (Mentha piperita) extracted from peppermint leaves is generally regarded as an excellent carminative and gastric stimulant, and also has been used in cosmetic formulations as a fragrance component and a general skin conditioning agent. The principal ingredient of peppermint oil, menthol, is primarily responsible for its beneficial effects In vitro, peppermint has been reported to show anti-inflammatory, antimicrobial, and antifungal activities as well as strong antioxidant activity, and antiallergenic and antitumor actions ,. Several clinical trials examining the effects of peppermint oil (PEO) on irritable bowel syndrome have been reported . However, experimental trial of PEO in its hair growth activity has not been fully reported. The aim of this study was to address the therapeutic potential of PEO for hair loss via the comparative analysis between PEO and minoxidil.

MATERIALS AND METHODS

Materials. This study used peppermint oil (Sanoflore®, France) certified as 100% pure and natural essential oil by an organic product certification organization (ECOCERT-F- 32600) and jojoba oil (Desert Whale, USA). The chemical compositions of peppermint oil and jojoba oil used are listed in Table 1. The 3% minoxidil was obtained from Hyundai Pharmacia (Korea).

Table 1.

Composition of peppermint oil and jojoba oil

Experimental animal. Five-week-old male C57BL/6 mice (Daehan Biolink Co., Korea) were allowed to adapt to their new environment for one week, with food and water provided ad libitum under 22 ± 1℃ room temperature, 50 ± 5% relative humidity and 12 hrs of a light/dark cycle before the experiment was begun. The dorsal area (2 cm × 4 cm) of the 6-week-old C57BL/6 mice was shaved with an animal clipper. Upon shaving the mice all of the hair follicles were synchronized in the telogen stage, showing pink color. All animals were randomized into 4 groups based on different topical applications: saline (SA), jojoba oil (JO), 3% minoxidil (MXD), and 3% peppermint oil (PEO, diluted in jojoba oil). Each compound (100 μl) was topically applied to the shaved dorsal area once a day, 6 days a week, for 4 weeks. Both animal care and the protocol for this study were in accordance with IACUC (Institutional Animal Care and Use Committee) and OECD guidelines.

Hair growth observation. To assess the hair growth in each group, photographs of the animals were taken at week 1, 2, 3, and 4 after topical application was begun. The hair growth effect was scored as follows, 0: no hair growth; 1: less than 20% growth; 2: 20% to less than 40% growth; 3: 40% to less than 60% growth; 4: 60% to less than 80% growth; and 5: 80% to 100% growth.

Histological analysis. The mice were euthanized with diethyl ether and extracted skin tissue. Number of mice sacrificed at week 1, 2, and 4 was and 3, 3, and 5, respectively, and their dermal skin samples were fixed in 10% buffered formalin for 24 hrs, followed by paraffin wax embedding using standard techniques. General histology was visualized by hematoxylin-eosin (H&E) staining, and we subsequently observed the number, elongation and depth of hair follicles by fluorescent microscopy (Axio imager, Carl Zeiss, Germany). The dermal thickness and follicle depth were also measured by using the scale bar tool of the fluorescent microscope.

Detection of alkaline phosphatase activity in dermal skin. The extracted dorsal skin was minced and homogenized with a homogenizer (T25 basic, IKA, Malaysia) by adding 4 times phosphate buffered saline (PBS) to give a 20% homogenate. The homogenate was centrifuged at 12,000 rpm, 4℃, for 20 min (AVANTI, Beckman Coulter Inc., USA). The supernatants were kept in a deep freezer at −80℃ and used for the assay. The activity of alkaline phosphatase (ALP) was analyzed with an auto biochemistry analyzer (Konelab 20XT, Thermo, Finland).

Isolation of total RNA and cDNA synthesis. Total RNA was isolated from the extracted dorsal skin using the High Pure RNA Isolation Kit (Roche Applied Science, Penzberg, Germany) following the manufacturer’s protocol. The quantity and quality of the isolated total RNA were determined by the UV/Vis spectrophotometer (Mecasys Co., Korea). Only samples with 2.0 > OD 260/280 > 1.8 were further analyzed. cDNA was synthesized from 1 μg of total RNA, using AccuPower CycleScript RT PreMix Kit (Bioneer, Korea) in a final volume of 205 μl.

Reverse transcription polymerase chain reaction. First, cDNA was diluted 1:10 with sterile deionized water, and 2 μl of the diluted cDNA was added to AccupowerTM PCR PreMix (Bioneer, Korea) and 10 pmol/L specific primer. This reaction mixture was filled up to a final volume of 20 μl with water. PCR was carried out in a PCR cycler (MycyclerTM thermal cycler, BioRad, USA). Cycling protocol for insulin-like growth factor-1 (IGF-1) was as follows: 1 cycle 94℃ for 5 min, followed by 35 cycles, 94℃ for 30 s, 60℃ for 30 s, 72℃ for 30 s, and a final extension at 72℃ for 5 min. Cycling protocol for GAPDH was as follows: 1 cycle 94℃ for 5 min, followed by 35 cycles, 94℃ for 30 s, 58℃ for 30 s, 72℃ for 30 s, and a final extension at 72℃ for 5 min. Reaction products were electrophoresed in 1.5% agarose gels and visualized with using ethidium bromide (EtBr). Each band was densitometrically quantified by image analyzer (Kodak 1D v3.6 image Analysis system, USA) and normalized with GAPDH intensity. The primer sequences used were as follows: IGF-1 forward 5′- AGAGACCCTTTGCGGGGCTGA-3′, reverse 5′-CTTCTGAGTCTTGGGCATGT- 3′; GAPDH forward 5′-AACGGATTTGGTCGTATTGG- 3′, reverse 5′-AGCCTTCTCCATGGTGGTGAAGAC- 3′.

Water and food intakes, food efficiency ratio and body weight change. The water and food intakes of experimental animals were measured once a week, and the weight was measured immediately before the experiment started and at 09:00~10:00 a.m. once a week during the experimental period.

Statistical analysis. The data were statistically analyzed by Student’s t-test for the comparison among groups using SPSS WIN (v21.0). The results were considered statistically significant if the p-values were less than 0.05.

RESULTS

Hair growth promotion. From week 2, PEO grew hair more rapidly than SA and JO. At week 3, PEO remarkably promoted hair growth than SA and JO, even greater than MXD. At week 4, PEO showed hair growth about 92%, whereas MXD about 55% (Fig. 1).

Fig. 1.

Comparison of the hair growth effect in C57BL/6 mice. The back skins of the mice were shaved and test compounds were topically applied for 4 wks. The hair growth effect was calculated using scoring index: 0~19% (1), 20~39% (2), 40~59% (3), 60~79% (4),

Hair growth promotion was evaluated by observing the darkening of the skin color, which indicated telogen to anagen conversion, bright pink in telogen and grey/black in anagen. At week 1, PEO changed the dorsal skin color from pink to grey/black and from week 2, it showed a considerably rapid increase in hair growth (Fig. 2). These results clearly demonstrate that the topical application of PEO induces rapid anagen hair growth in telogen mouse skin.

Fig. 2.

Gross observation of back skins in C57BL/6 mice. The back skins of the mice were shaved and test compounds were topically applied for 4 wks. SA; saline, JO; jojoba oil, MXD; 3% minoxidil, PEO; 3% peppermint oil.

Increase of dermal thickness, hair follicle number and hair follicle depth in histological analysis.Histological analysis showed that 4-wk topical application of PEO and MXD induced very thick and long hair growth and promoted the elongation of hair follicles from dermis to subcutis (Fig. 3). These results indicate that the hair follicles of PEO and MXD groups at week 4 were in the anagen stage. We also observed a slight increase of epidermal thickness in PEO group.

Fig. 3.

Histological observation of hair follicles in C57BL/6 mice. The back skins of the mice were shaved and test compounds were topically applied for 4 wks. H&E stain, ×100. Scale bar 200 μm. (A) transverse view of hair follicles, (B) 

At week 2, PEO showed dermal thickness to 95% and 66% greater than SA and JO, respectively (p < 0.01). At week 4, PEO showed it to 120% and 81% greater than SA and JO, respectively (p < 0.01), comparable to MXD (Fig. 4).

Fig. 4.

Change of dermal thickness in C57BL/6 mice. The back skins of the mice were shaved and test compounds were topically applied for 4 wks. The dermal thickness was measured by the average of two different points in the field with an eyepiece of ×100 

Fig. 5 shows the growth promoting activity of hair follicle number. At week 2, the hair follicle number of PEO group was 473% and 218% greater than SA and JO groups, respectively (p < 0.05). At week 4, PEO group had 740% and 307% more hair follicles than SA and JO groups, respectively (p < 0.001), comparable to MXD group. We also found that the number of hair follicles increased as hair regrew.

Fig. 5.

Change of follicle number in C57BL/6 mice. The back skins of the mice were shaved and test compounds were topically applied for 4 wks. The follicle number was determined by the average of two different points in the field with an eyepiece of ×100 

Fig. 6 shows the growth promoting activity of hair follicle depth. At week 2, the depth of hair follicles of PEO group was 172% and 133% greater than SA and JO groups, respectively (p < 0.01). At week 4, the depth of hair follicles of PEO group was 236% and 182% greater than SA and JO groups, respectively (p < 0.001), comparable to MXD. Histological studies revealed that PEO markedly stimulated the skin and thickened it. The depth, size, and number of hair follicles were also markedly increased in PEO treated skin. These results clearly demonstrate that topical application of PEO markedly stimulated hair growth and induced rapid anagen hair growth in telogen mouse skin.

Fig. 6.

Change of follicle depth in C57BL/6 mice. The back skins of the mice were shaved and test compounds were topically applied for 4 wks. The follicle depth was measured by the average of two different points in the field with an eyepiece of ×100 

Change of ALP enzyme activity with hair cycle. At week 2, PEO showed 253% (p < 0.05), 35%, and 13% greater ALP activity compared to SA, JO, and MXD, respectively (Fig. 7). At week 4, PEO showed 192% (p < 0.05), 90%, and 13% greater ALP activity compared to SA, JO, and MXD, respectively. After topical application on the backs of C57BL/6 mice for 4 wks, PEO induced the earliest telogen-to-anagen conversion, with MXD, JO and SA following in order. The increase in ALP activity of PEO group was fast compared to MXD group, with remarkably significant compared to SA and JO groups.

Fig. 7.

Change of skin ALP activity in C57BL/6 mice. The back skins of the mice were shaved and test compounds were topically applied for 4 wks. Values are the mean ± SD of 3, 3, and 5 mice at week 1, 2, and 4, respectively. The value is significantly 

Comparison of IGF-1 mRNA expression. At week 2, PEO showed 33% and 21% greater IGF-1 mRNA expression compared to SA and JO, respectively (p < 0.05) (Fig. 8). At week 4, PEO showed 89% (p < 0.001) and 34% (p < 0.01) greater IGF-1 mRNA expression compared to SA and JO, respectively, comparable to MXD. PEO showed remarkably increased IGF-1 mRNA expression, even better than MXD.

Fig. 8.

Change of IGF-1 expression in C57BL/6 mice. The back skins of the mice were shaved and test compounds were topically applied for 4 wks. Values are the mean ± SD of 3, 3, and 5 mice at week 1, 2, and 4, respectively. The value is significantly 

Change of water and food intakes, food efficiency ratio, and body weight. Body weight gain, food efficiency, and weight of MXD group were higher than the other groups but did not show significant difference (Table 2 and Fig. 9).

Table 2.

Daily water intake, food intake, body weight gain, and food efficiency ratio in C57BL/6 mice applied with test compounds for 4 wks
Fig. 9.

Change of body weight in C57BL/6 mice. The back skins of the mice were shaved and test compounds were topically applied for 4 wks. Values are the mean ± SD of 11 mice. SA; saline, JO; jojoba oil, MXD; 3% minoxidil, PEO; 3% peppermint oil.

DISCUSSION

MXD has been widely used to treat androgenetic alopecia, but little is known about its pharmacological activity or about the identity of its target cells in hair follicles . Topically applied MXD was believed to stimulate hair growth by indirect drug action, i.e. by inducing vasodilatation and increasing blood flow to the follicular dermal papilla cells, or by creating a local irritation . The follicular dermal papilla cells are the most likely target site for the action of MXD . Mori and Uno  reported that topical application of MXD specifically stimulates the secondary germ of the telogen follicles, resulting in their rapid progression to anagen follicles. Thus, hair follicle is useful marker that is associated with hair cycle . Anagen I-VI development is characterized by increasing length of the hair follicle and catagen I-VII by decreasing length. During telogen, the hair follicle reaches its minimal length. Synchronized hair follicle cycling in mice is also associated with stage-dependent changes in dermal thickness. A hair follicle in telogen, anagen I or anagen II has not yet reached the subcutis. During the anagen III stage, the follicles move from the dermis down to the subcutis.

We found that PEO remarkably promoted hair growth compared to SA and JO, even faster than MXD without significant change of body weight gain and food efficiency. Chen et al reported that MXD took only about 10 days for the hair of mice to fully regrew after the topical application of MXD, indicating the enhancing effect of MXD in the proliferative rate of hair growth. In our study, histological analysis showed that MXD promoted hair growth in terms of hair follicle number, follicle depth, and dermal thickness at week 2.

Menthol is a major constituent of peppermint oil, which is a cyclic alcohol. Menthol has been widely used as a component of food and cosmetics. It has been reported that menthol increases the sensitivity of cutaneous cold receptors by modulating Ca2+ currents of neuronal membranes . Menthol is the most effective penetration enhancer that, along with limonene, can be considered the prototype for the use of terpenes as penetration enhancers . For years terpenes (e.g., menthol, β-pinene, terpinene-4-ol, α- pinene, 1,8-cineole) have been used alone or as constituents of essential oils in medicine, cosmetics and household products. In the experimental dermopharmacy and technology of transdermal drug forms, terpenes have also been intensively explored as penetration enhancers . When skin is treated with terpenes, the existing network of hydrogen bonds between ceramides may loosen because of competitive hydrogen bonding . The high accumulation of most of the terpenes in the skin layers proves that these compounds easily permeate the stratum corneum and that they may easily penetrate into blood circulation in vivo .

In our study, we found that PEO induced very thick and long hair after 4-week topical application and promoted the elongation of hair follicles from the epidermis down to the subcutis in a vertical section (Fig. 3), showing in the stage of anagen III. Application of MXD caused similar results. We observed that this increase in hair follicle length was not associated with any loss of hair follicle architecture and that the increase in hair follicle length was associated with an increase in the length of the keratinized hair shaft.

The drugs for alopecia treatment have been developed to maintain or induce the anagen stage of hair cycle. ALP activity was particularly detected in the dermal papilla. ALP activity in the dermal papilla was moderate in very early anagen, reached a maximal level in early anagen, and was kept at a low level during catagen . The bulbar dermal sheath showed intense ALP activity only in early anagen . Although results from clinical trials vary, the majority of the evidence indicates that there is a direct correlation between the hair follicle depth and the level of ALP activity. In our study, PEO induced significantly high ALP activity at week 2, even greater than MXD. This study demonstrates that PEO stimulates both dermal papilla and ALP activity, which promotes blood circulation by relaxing vascular smooth muscle .

To better understand the influence of the endocrine system in hair growth, we analyzed the mRNA expression of IGF-1 gene. It is a potent mitogen supporting cell growth and survival  and also plays a role to increase hair thickness . In our study, PEO showed remarkably increased IGF-1 mRNA expression at week 2, whereas MXD at week 4.

In conclusion, our experimental data suggest that 3% PEO facilitates hair growth by promoting the conservation of vascularization of hair dermal papilla, which may contribute to the induction of early anagen stage. In addition, PEO effectively stimulated hair growth in an animal model via several mechanisms and thus could be used as a therapeutic or preventive alternative medicine for hair loss in humans.

Benefits of Oil of Oregano

Some of the Health Benefits of Oregano Oil:

The ancient Greeks were the first people to identify the oil of oregano benefits for its health and medicinal properties. It is potent, anti-viral, anti-bacterial, antifungal and anti-parasitic oil with a range of health benefits.

  • Contains Powerful Phenols: Most of the health benefits of oregano oil can be attributed to the presence of carvacrol and thymol compounds as they have the ability to kill harmful microbes in the body. These powerful phenols have anti-bacterial, anti-viral, anti-parasitic, and anti-fungal properties. It’s important that the carvacrol concentration be at least 70%.
  • Anti-Oxidant & Anti-Inflammation Properties: Inflammation is caused as a result of the body’s natural response to toxins, injury and infections and can cause degeneration of the body’s systems. The oil of oregano possesses anti-oxidant and anti-inflammatory properties which prevent inflammation, thus strengthening the body’s resistance.
  • Good Anti-Oxidant: Oregano oil contains decent amounts of antioxidant polyphenols, rosemarinic acid and quercitin. Research has proved that the oxygen radical absorption capacity (ORAC) in this oil is 4 times greater than that of blueberries and higher than vitamin E. The higher the ORAC value, the higher the antioxidant levels are, thus improving the healing potential.
  • Lowers Risk of Heart Diseases: Due to its antioxidant properties, oregano oil is effective in protection against the oxidation of LDL (bad) cholesterol, thus reducing the risk of heart diseases.
  • Prevents Cancer: The antimutagenic and anticarcinogenic effects of oregano oil help in prevention of cancer.
  • Improves Body’s Defense Mechanism: Oregano oil is an excellent option for increasing the body’s defense mechanism against cold or sore throat. You can simply take 3 drops of oregano oil in a day or mix it into a glass of orange juice and notice results within a few hours. Oregano oil should be taken up to 5 days to totally eliminate the symptoms.
  • Relieves Sinus Congestion: Oregano oil is a natural remedy for sinus congestion. You can add 3 drops of oil into a glass of juice and drink this mixture daily for 3 to 5 days for relief.
  • Digestive Aid & Expectorant: Due its high content of thymoland carvacrolcompounds, oregano oil is effective in calming upset stomach and aids in digestion. Indigestion can be cured by drinking a glass of milk or juice that is mixed with 2 or 3 drops of oregano oil. It also acts as an expectorant to rid the lungs, bronchi and trachea of excess mucus.
  • Sedative: This oil is a strong sedative and small doses can have a soothing effect and aid peaceful sleep.
  • Topical Application Agent: Oregano oil can be topically applied on the skin to cause internal healing. Thus, swollen lymph nodes, sore throat and ear infections can be cured by rubbing the oil directly on the affected area.
  • Heals Mind & Body: The healing benefits of oregano oil can be further experienced by massaging the soles of your feet with this oil. This is beneficial to the entire body systems and has been traditionally used for healing the mind and the body. Besides, it is an alternative method of clearing the body of viral and fungal infections.
  • Treats Pneumonia: This oil is extremely beneficial in case of pneumonia. For this purpose, diffuse it and inhale from a bowl of steaming water. It should also be applied on the soles of your feet.
  • Treats Nasal Polyp: Oregano oil should be considered if you are suffering from nasal polyp. Add 2 drops of oregano oil in a pan of steaming water. Placing a towel over your head, inhale the steam for as long as possible. It can also be applied on the reflex points of your feet.
  • Cures Whooping Cough: Massaging oregano oil over the chest and into the pads of the feet and/or diffusing it through the air can provide relief from whooping cough.
  • Treats Muscle Aches: In case of muscle aches, you can massage your muscles with oregano oil diluted in coconut oil, moving towards your heart.
  • Treats Viral & Fungal Infections: Topical application of this oil is beneficial in the treatment of warts, fungal nail growths pimples, cold sores etc. However, it is advisable to do a skin patch test first to find out the correct dose.
  • Cures Gastrointestinal & Bronchial Infections: This oil helps in curing gastrointestinal and bronchial infections. Carvacol and Thymol compounds act as antibacterial and antispasmodic agents to stimulate bile flow in the gall bladder. Hence, it is effective in the treatment of urinary tract infections, respiratory tract ailments, menstrual cramps, arthritis, dyspepsia and bloating.
  • Good Antiseptic: Thymol , being an antiseptic, helps in treating gum disorders and toothaches and hence is used as an ingredient in toothpastes and mouthwashes.

Skin Benefits of Oregano Oil: Being a strong and effective blood purifier, antioxidant and rich in vitamins and minerals, oregano oil is beneficial for your skin. Topical application of this oil in a diluted form is known to treat skin infections, itches and irritations. Given below are some of its skin benefits.

  • Treats Skin Conditions: The carvacrolcompound in oregano oil helps in treating minor skin problems such as acne, cold sores, rashes and fungal infections when applied topically. This oil can be applied directly on acne lesions to speed up the healing process. The tingling sensation observed after the application of this oil stops the herpes virus from manifesting altogether. You can also mix 2 -3 drops of this oil in a glass of water and dab on the acne with a cotton ball. Discontinue using it if you discover redness or irritation.
  • Anti-Bacterial: Since it possesses anti-bacterial properties, it has the ability to destroy candida and other unknown bad germs causing skin infections. It can be taken in a capsule, added to food or massaged over the affected area.
  • Cures Athlete’s Foot: In case of athlete’s foot, you can massage your feet with oregano oil, add a drop of oil to your shoes or soak your socks in warm water and 2 drops of oregano oil for relief.
  • Delays Signs of Ageing: Taking oregano oil every day can provide anti-aging benefits by removing signs of aging and delaying the aging process resulting in a brighter skin color.
  • Used in Spa: Oregano oil possesses anti-bacterial, anti-inflammatory, anti-microbial, anti-viral and anti-fungal properties which destroy the free radicals that damage healthy cells, thus curing acne, psoriasis and nail fungus. It is one of the most effective inhibitors of yeast infections.
  • Treats Calluses: Calluses can be treated by massaging the affected area with oregano oil diluted in coconut oil.

Pure oregano oil is extremely beneficial for hair and can heal scalp conditions which affect hair growth. This oil can be either ingested in the form of capsules or applied topically on the scalp. Since it is highly concentrated, it should be used in a diluted form with other carrier oils like coconut, olive, jojoba, tea tree oils etc. It’s actually been known to cure dandruff and stimulate hair growth. Mix a few drops of pure oregano oil per tablespoon of shampoo. Alternatively, you can create a topical ointment mixing an ounce of pure oregano oil with 4 ounces of coconut oil and apply it on the scalp after washing and conditioning your hair.

One must be careful while using or consuming it. It should be taken in small doses. Pregnant women should refrain from using internally!!!

Rosemary oil vs minoxidil 2% for the treatment of androgenetic alopecia: a randomized comparative trial.

Abstract

Rosmarinus officinalis L. is a medicinal plant with diverse activities including enhancement microcapillary perfusion. The present study aimed to investigate the clinical efficacy of rosemary oil in the treatment of androgenetic alopecia (AGA) and compare its effects with minoxidil 2%. Patients with AGA were randomly assigned to rosemary oil (n = 50) or minoxidil 2% (n = 50) for a period of 6 months. After a baseline visit, patients returned to the clinic for efficacy and safety evaluations every 3 months. A standardized professional microphotographic assessment of each volunteer was taken at the initial interview and after 3 and 6 months of the trial. No significant change was observed in the mean hair count at the 3-month endpoint, neither in the rosemary nor in the minoxidil group (P > .05). In contrast, both groups experienced a significant increase in hair count at the 6-month endpoint compared with the baseline and 3-month endpoint (P < .05). No significant difference was found between the study groups regarding hair count either at month 3 or month 6 (> .05). The frequencies of dry hair, greasy hair, and dandruff were not found to be significantly different from baseline at either month 3 or month 6 trial in the groups (P > .05). The frequency of scalp itching at the 3- and 6-month trial points was significantly higher compared with baseline in both groups (P < .05). Scalp itching, however, was more frequent in the minoxidil group at both assessed endpoints (P < .05). The findings of the present trial provided evidence with respect to the efficacy of rosemary oil in the treatment of AGA.

Using Castor Oil for Hair Growth – Can It Really Help?

Castor seeds and oil in a wooden bowl

In this article, I’ll explain why castor oil is indicated as an effective hair loss treatment method, and how you can use castor oil for hair growth yourself.

You’re going to learn about ricinoleic acid, an omega-9 fatty acid which makes up the majority of castor oil’s composition.

Further, you’ll discover how scientific research has indicated its possible use as an inhibitor of PGD2, a compound found to be present in overabundance within the scalps of men with androgenetic alopecia.

Then, I’ll teach you the exact best way to apply castor oil to your scalp for maximum benefits.

Finally, I would recommend taking my new 6 part questionnaire to calculate your chances of naturally re-growing your hair. The higher your score the more likely that castor oil and other natural methods will successfully work for you.

Flowering castor oil plant, ricinus communisWhat is Castor Oil?

A vegetable oil obtained through the pressing of the seeds of the castor oil plant, castor oil is used in a variety of industries and is known for its mold-inhibiting and lubricating abilities.

Now found in tropic regions throughout the world, the castor oil plant is native to the Mediterranean Basin, Eastern Africa, and India.

The flowers of this glossy-leaved plant range in color from yellowish-green to red, and its size can vary tremendously.

Not-so-fun fact: Consumption of castor beans can be fatal. This is due to the levels of ricin found within the bean.

Castor oil, however, does not contain ricin, as the process of oil extraction heats up the protein to such an extent as to denature and inactivate it.

What really makes this plant so special, however, is the abundance of ricinoleic acid which is present within its oil. Ricinoleic acid makes up 89.5% of castor oil’s fatty acid composition and has various properties which lend themselves to effective treatment of hair loss.

Can Castor Oil Be Used to Treat Hair Loss?

When it comes to answering this question, I like to look at the cold, hard facts.

While I’ll be delving into the scientific research in the next section, consider these facts about castor oil:

Castor oil contains high amounts of ricinoleic acid, an omega-9 fatty acid which has been shown to have anti-inflammatoryantimicrobial, and antioxidant properties.

castor oil for hair growth

The castor seeds and oil.

These properties alone make ricinoleic acid and, therefore, castor oil, a treatment option to be considered by those with alopecia.

Inflammation of the scalp constricts blood flow to the hair follicle, reducing the levels of necessary nutrients. Additionally, inflammation can be a direct cause of hair loss, especially for those with scarring alopecia.

Ricinoleic acid, however, has been shown to have anti-inflammatory effects, similar to capsaicin, but without an increase of blood flow to the applied area, which can cause irritation.

Further, ricinoleic acid’s antimicrobial abilities may provide relief to hair loss sufferers who are struggling with bacterial or fungal infections of the scalp.

Application of castor oil can treat the infection and ensure that your scalp and hair follicles stay clean, healthy, and free from infection.

And, as if inflammation and infection weren’t enough, free radicals are another contributor to hair thinning and loss. Ricinoleic acid’s free radical scavenging abilities, however, can help you to reduce the levels of cell damage within your scalp.

What Does the Research Have to Say?

While human studies on the use of castor oil in the treatment of alopecia are lacking, there are a few studies which compel me to believe that castor oil is a viable option for hair loss treatment.

I previously discussed the role which Prostaglandin D2 plays in hair loss, but here’s a quick recap:

A 2012 study conducted by Garza et al discovered a link between PGD2 elevation and hair loss, first in mice and then in men.

Initially, Garza and his team tested their theory on mice.

Two groups of mice were used, both of which received an initial topical application of 15-dPGJ2 in order to synchronize the hair follicle cycles of all mice.

On day 8, however, only one group received another application of the 15-dPGJ2while the control group received an acetone vehicle.

The hair lengths of the mice were measured on days 4, 12, 14, and 16, and as is clear in the tables below, the mice which received the additional 15-dPGJ2 treatment had shorter hair lengths than those mice in the control group.

PGD2 levels effect on hair growth in mice

PGD2 levels of mice in the control group and mice who received an application of15-dPGJ2 (A-C). The effects of PGD2 and 15-dPGJ2 on human hair growth (D).

Additionally, researchers looked at the effects of PGD2 and 15-dPGJ2 on human hair follicles. Extracted follicles were maintained in culture for 7 days, where increasing amounts of vehicle, PGD2, or 15-dPGJ2 were applied.

The results of this particular test can be seen in figure 6D above.

Through this study, researchers formed the theory that the GPR44 receptor is to blame for PGD>sub>2 and 15-dPGJ2’s inhibitory activities.

Researchers were also interested in the levels of PGD2 present in men with androgenetic alopecia (AGA) and those without.

PGD2 levels in haired men vs bald men results

The levels of PGD2 and 15-dPGJ2 in haired men vs. bald men.

Through the use of mass spectrometry, the researchers were able to determine the levels of PGD2 within the studied men. In the balding men, the levels were 16.3 ng/g tissue, while in men with hair, the levels were 1.5 ng/g.

Androgens and Prostaglandins: A Cascade Effect

It seems quite obvious through the provided research that high levels of PGD2 are present in the scalps of balding men when compared to their haired counterparts. That, of course, begs us to ask whether this is a chicken-or-egg

arachidonic acid cascade and production of PGD2

A simplified version of the arachidonic acid cascade showing how the enzyme, prostaglandin D synthase (PTGDS), converts PGH2 to PGD2.

scenario. In other words, does an over-production of PGD2 lead to hair loss, or does hair loss, in some way, trigger the overproduction?

PGD2 is actually an important player in the development of the male reproductive system. PGD2production is fueled by testosterone through a process known as the arachidonic acid cascade.

Unfortunately, this process can sometimes lead to the overproduction of PGD2, known to slow hair growth, while simultaneously under-producing PGE2, a prostaglandin which is actually linked to hair growth induction.

This imbalance leads to the triggering of Gpr44, the receptor mentioned above which is believed to be responsible for PGD2’s ill effects.

This entire process, ultimately, results in one thing: slowed hair growth.

If the overproduction of PGD2 plays a role in hair loss, then what can be done to prevent its unwanted effects?

Ricinoleic Acid: An Inhibitor of PGD2

While clinical trials are underway to test the effectiveness of various pharmaceutical drugs on their abilities to reduce the effect of PGD2 by blocking the GPR44 receptor, a recent study by researchers in China shows that castor oil may provide a natural and readily-available alternative.

Fong et al selected 12 herbs commonly used in Traditional Chinese Medicine and tested various aspects of each.

The aim of the study was to determine whether any of the 12 herbs or their constitutents were inhibitors of prostaglandin D2 synthase (PTDGS) and, therefore, could be developed for use in the treatment of androgenetic alopecia (male-pattern baldness).

chemical structure of ricinoleic acid - inhibitor of PGD2

Two-dimensional structure of ricinoleic acid.

One of the herbs which was tested was, you guessed it, castor. Or, ‘ricinus communis’ as it was identified in the study.

As discovered by researchers, ricinoleic acid, a major component of castor, has a few properties which made it stand out as a potentially effective inhibitor of PDG2.

First and foremost, ricinoleic acid received a high docking score as tested by researchers.

Docking is an indicator of inhibitory prowess, as it shows an ability to interact and bind. In fact, the similarity in chemical structures between ricinoleic acid and prostaglandin is a good indicator of its ability to interact and bind with the molecule.

The striking similarities can be seen by comparing the below prostaglandin structures with the above image of ricinoleic acid.

chemical structure of prostaglandins

The chemical structures of three prostaglandins: PGE2, PGF2, and PGD2.

Second, ricinoleic acid has excellent skin permeability. This is important for the exertion of its pharmacological effects.

Third, ricinoleic acid has minimal adverse effects when applied topically.

With this information in hand, researchers concluded that ricinoleic acid, along with four other TCM constituents, show potentially strong inhibitory properties as it relates to PGD2, though further research is required.

How to Include Castor Oil In Your Hair Care Routine

While the consumption of castor oil can have undesirable effects, direct application to the scalp can prove to be an effective way to boost hair growth and improve the overall quality of your scalp and hair.

Make Your Own Shampoo

One shampoo that I go back to again and again is my maple syrup and carrot seed recipe. The combination of ingredients is excellent for individuals looking to fight hair loss and reap the benefits of a healthy scalp.

Ingredients:
● Liquid castile soap (1/2 cup)
● Maple syrup (2 tablespoons)
● Carrot seed essential oil (5-10 drops)
● Castor oil (10 drops)

Method:
Mix the ingredients thoroughly. Apply evenly to your wet scalp, working the mixture in with your fingertips for 2-3 minutes.

Rinse thoroughly.

Hair Benefits:
The soothing effects of the maple syrup, combined with the scalp-stimulating and antifungal properties of the carrot seed oil, make this shampoo an essential addition to your hair care rotation.

Apply It Directly to Your Scalp

Beginning with a palm-sized amount, work the castor oil through your hair from rApply castor oil to hair and scalpoot to tip. Continue adding small amounts of castor oil until your hair and scalp are covered, but not saturated.

You can leave the castor oil in overnight, or rinse thoroughly 20-30 minutes after application.

Tip: As castor oil is thicker than other oils you may have applied previously, like olive oil or canola oil, you will want to apply in small, incremental amounts to avoid over-application.

This will make rinsing of the oil easier. Additionally, you can combine castor oil with other oils, such as grapeseed, to reduce the viscosity and make it easier to apply and spread throughout your hair.

Are There Side Effects Associated with Castor Oil Supplementation?

Castor oil, when consumed, is known to have laxative effects. An over-consumption of castor oil can lead to intestinal cramping and nutrient malabsorption, and should be avoided.

castor oil and castor plant seeds

An allergic reaction, while rare, can occur upon application of castor oil to the skin.

Prior to use on your scalp, it’s recommended that you first test on a small area of skin. If you experience itchy, hives, rash, redness, or hotness, avoid further application.

While castor oil’s effects on labor induction are still debated, the consumption of castor oil by pregnant woman has been shown to induce nausea.

Women who are pregnant should consult with their medical professional prior to use.

Conclusion

The studies have shown that, while the overproduction of PDG2 is linked to slowed hair growth and eventual hair loss, ricinoleic acid, the main component of castor oil, is indicated as a possible inhibitor of the compound.

While further testing is required to determine ricinoleic acid’s PDG2-inhibiting abilities in vivo, there is no doubt as to the fatty acid’s anti-inflammatory, antimicrobial, and antioxidant abilities.

This alone makes castor oil a treatment option for individuals looking to fight hair fall.

If you’re looking to find treatment for aggressive hair loss, however, then castor oil is not it.

Its listed properties may be beneficial in terms of scalp health and cleansing, but there are no indications that castor oil can totally reverse hair loss.

Instead, castor oil used frequently can help to prevent further hair loss and create a hygienic environment in which hair can grow.

Jojoba Oil for Hair: How It Works

What is jojoba oil?

Jojoba oil is an oil-like wax extracted from the seeds of the jojoba plant.

The jojoba plant is a shrub native to the southwestern United States. It grows in the desert regions of Arizona, southern California, and Mexico.

Manufacturers began adding the oil to cosmetics and food in the 1970s. It’s incredibly versatile, and its uses are too numerous to count. One of its most popular purposes is for cosmetics. It’s found in a variety of hair, skin, and nail products.

Today, you’re most likely to find jojoba oil in beauty and hair care products of many kinds.

BENEFITS

Why do some people use jojoba oil for hair?

Jojoba oil has an oily composition, so it can be used as a moisturizer. It can also be added to hair conditioners to give you added protection against dryness, breakage, and split ends.

The oil can also moisturize the scalp and may be a dandruff remedy.

Jojoba is rich in vitamins and minerals that nourish hair, including vitamin C, B vitamins, vitamin E, copper, and zinc.

Because it strengthens hair, it is also thought that jojoba oil can prevent hair loss and promote hair thickness. The idea behind this is that the oil moisturizes hair follicles, which prevents dryness that leads to hair loss.

RESEARCH

What’s the research on jojoba oil for hair?

There are many claims around jojoba oil and what it can do for your hair. Some are accurate and supported by research, while others may be a bit far-fetched.

Jojoba’s use as a moisturizer for hair and skin is its main benefit, with a recent dermatological reviewconfirming this. Recent patents also include it as a staple ingredient in most shampoos and conditioners, arguing for its inclusion as an important microemulsion in hair care products. Microemulsions help carry the active ingredients in the product. Other common microemulsions are beeswax, carnauba wax, or esparto grass wax.

For this reason, jojoba oil may indeed prevent hair breakage and strengthen your locks. It could also be helpful in treating dandruff, dry scalp, and itchy scalp, and be used as an anti-inflammatory and skin moisturizer as well.

The oil’s reputation as a direct hair growth stimulant, on the other hand, is not supported by research. One recent study that tested jojoba oil for hair growth found that it was less effective than minoxidil(Rogaine) and peppermint essential oil.

For this reason, jojoba oil should not be relied on as a therapy for pattern baldness (male or female), alopecia, or other hair loss disorders. Still, it can be a great product for promoting strong, silky, and shiny hair.

Cedar Wood Oil for Hair Growth

Cedar wood pines and a bottle of oil

Everyone knows stress can lead to hair loss, but the unfortunate fact is that hair loss also leads to stress. This is a vicious cycle, but with the right products and information, you can maintain your head of hair.

There are tons of miracle creams and magical hair growth formulas on the market. A majority of these are fake, do not work as well as intended, or are just down right lying about their product.

Rather than buying hundreds of products on a whim and trying them all, you should be doing research and deciding which ones are worth your time and money.

This article will give an in depth explanation of one of the natural, organic ways to achieve the hair you desire. This product is called cedar wood oil. This article will help you understand what this oil is, where it comes from, how it works, who should be using it, and where you can buy it.

What is Cedar Wood Oil?

Cedar wood oil, or just simply cedar oil, is what is known as an essential oil. This means it is a hydrophobic, does not mix with water, oil made up of volatile compounds from plants (7).

Essential oils are also known as volatile oils, ethereal oils, or just simply plant oils. Cedar wood oil is the oil derived from various coniferous trees.

Most of these oils come from the trees in the pine family or cypress family (7). The needles and other foliage tend to be what is used for extracting this oil.

 

It is also common to use leftover tree pieces such as the bark, roots, and stumps that were not taken during a time of timbering to get cedar wood oil.

Even though it is called cedar, some of the most important nutrients actually come from cypress and juniper trees rather than the name would suggest.

It has been around for literally thousands of years as well. Ancient civilizations dating all the way back to the Egyptians and Sumerians have records showing their use of cedar oil.

These peoples actually got their oil from what are called the Cedars of Lebanon, or cedrus labini (7).

Almost entirely destroyed now, these trees were the complete and total source of cedar oil for ancient people, but they are no longer used at all. This is where the name for the oil came from.

Cedar oil has many helpful benefits, but possibly the greatest comes in the form of cedrol. A cedar oil with a higher amount of cedrol present will in turn have a higher pesticide effect on insects.

This is exactly why the ancient people primarily used this oil during the embalming process to keep bugs away from the bodies (7).

However, we now have an understanding of far more uses for the cedar wood oil. It is good for everything from toothaches and cough reduction to the promotion of hair growth and acne cures.

Cedar wood oil has a great number of uses and can be a great tool to add to your cosmetic arsenal (7).

How Effective is Cedar Wood Oil?

It has been scientifically proven that when combined with a few other natural oils cedar wood oil is capable of promoting hair growth.

A 1998 Scottish study at the Department of Dermatology studied the effects of oils on people who suffered alopecia areata.

Alopecia areata is a disease that causes the hair follicles to stop working but not die (1). This leads to baldness.

The double blind study showed an improvement is hair growth for 44% of those tested. The changes were quite noticeable as the patients’ hair was restored in length, thickness, and even color (1).

Cedar Wood Oil for Hair

Essential oils have been known to both curb hair loss and also stimulate the growth of new hair. Hair loss can be onset by many different factors.

These include damaged hair follicles and shafts. The cedar oil is a perfect way to combat these issues.

Poor circulation to the scalp is one of the leading causes of hair follicle weakening (4). Cedar oil is a great way to get blood flowing in your scalp again.

This increased stimulation will promote hair growth and overall strengthening of the hair. It also is a form of protecting your scalp from fungal infections that could lead to hair loss.

Cedar oil’s pesticide qualities can be a wonderful solution to funguses that will prevent your hair from coming in evenly and healthily (4). This will also prevent hair from falling out in the future. The stronger follicles lead to stronger and longer lasting hair.

It is also commonly found as an aftershave and an anti-acne treatment. Its astringent properties make it work very well at fighting against oily skin.

It has an enjoyable fragrance to many people and has a calming effect on bumps and pimples. Its oils help to solve the problem of razor burn and other facial problems (5).

What is Clary Sage Oil?

Scientific Name: Salvia sclarea

Clary sage oil is an essential oil extracted from the herb clary sage. The leaves and flowering tops of the plant are steam distilled to get the precious essential oil. It is very potent since it is an essential oil, so make sure to dilute it properly before use. A 2% dilution rate is the safe and recommended dilution for adults. This means for 1 tsp of vegetable oil/base ingredient, add just 2 drops of clary sage oil, not more.

Here are some of the properties of clary sage oil: Antidepressant, anticonvulsive, antispasmodic, antiseptic, aphrodisiac, astringent, bactericidal, carminative, deodorant, digestive, emmenagogue, euphoric, hypotensive, nervine, sedative, stomachic, uterine and nerve tonic.

Let’s now take a look at the benefits of clary sage oil for hair growth and more below!

Benefits of Clary Sage Oil for Hair

Clary sage oil offers the following benefits for hair:

  • Stimulates the hair follicles thus increasing blood circulation and promoting hair growth
  • Promoting a healthy scalp
  • Balancing scalp oils
  • Making hair shiny
  • Strengthening hair strands
  • Balancing hormones hence solving hormonal hair loss
  • Fights dandruff
  • Naturally conditions hair
  • Gives hair a nice scent

In ancient times, spikenard (also called nard, nardin and muskroot) was regarded as one of the most precious oils. It’s been used as a perfume, a medicine and in religious contexts across a wide territory from India to Europe. Biblically, it’s referenced when Mary of Bethany spent a year’s worth of wages to buy this oil and anoint Jesus’ feet before the Last Supper. It’s derived from Nardostachys jatamansi, a flowering plant of the Valerian family.

Spikenard oil is used as an herbal medicine to naturally treat insomnia, stress, digestive problems, weak immune system and infections. In Ayurvedic medicine, it’s used for treating sleeping troubles, depression, stress, anxiety, chronic fatigue syndrome and nervous problems. The powdered stem of this beneficial plant is taken internally to cleanse the uterus, help with infertility and treat menstrual disorders.


Spikenard Plant and Components 

Spikenard grows in the Himalayas of Nepal, China and India; it’s found at altitudes of about 10,000 feet. It grows to be about three feet in height, and it has pink, bell-shaped flowers. Spikenard is distinguished by having many hairy spikes shooting out from one root, and it’s called “the Indian spike” by the Arabs.

The stems of the plant, called rhizomes, are crushed and distilled into an essential oil that has an intense aroma and amber color. It has a heavy, sweet, woody and spicy odor, which is said to resemble the smell of moss. It blends well with frankincensegeranium, patchouli, vetiver and myrrh oils.

Spikenard essential oil is extracted by steam distillation of the resin obtained from this plant — its chief components include aristolene, calarene, clalarenol, coumarin, dihydroazulenes, jatamanshinic acid, nardol, nardostachone, valerianol, valeranal and valeranone. According to research, the essential oil obtained from the roots of spikenard show fungi toxic activity, antimicrobial, antifungal, hypotensive, antiarrhythmic and anticonvulsant activity. The rhizomes extracted with 50 percent ethanol show hepatoprotective, hypolipidemic and antiarrhythmic activity.


8 Proven Spikenard Benefits

1. Fights Bacteria and Fungus

Spikenard stops bacterial growth on the skin and inside the body. On the skin, it’s applied to wounds in order to kill bacteria and heal cuts fast. Inside the body, spikenard treats bacterial infections in the kidneys, urinary bladder and urethra. It’s also known to treat treat toenail fungus, athlete’s foot, tetanus, cholera and food poisoning.

A study done at the Western Regional Research Center in California evaluated the bactericidal activity levels of 96 essential oils. Spikenard was one of the oils that was most active against C. jejuni, a species of bacteria commonly found in animal feces. C. jejuni is one of the most common causes of human gastroenteritis in the world. Spikenard is also antifungal, so it promotes skin health and helps heal ailments caused by fungal infections. This powerful plant is able to ease itching, treat patches on the skin and treat dermatitis.

2. Relieves Inflammation

The spikenard essential oil is extremely beneficial to your health because of its ability to fight inflammation throughout the body. Inflammation is at the root of most diseases and dangerous for your nervous, digestive and respiratory systems; it’s known to play a role in allergic diseases like asthma, arthritis and Crohn’s disease, as well as Alzheimer’s disease, cancer, cardiovascular disease, diabetes, high blood pressure, high cholesterol levels and Parkinson’s disease.

A 2010 study done at the School of Oriental Medicine in South Korea investigated the effect of spikenard on acute pancreatitis — a sudden inflammation of the pancreas that can range from mild discomfort to a life-threatening illness. The results suggest spikenard treatment weakened the severity of acute pancreatitis and pancreatitis-associated lung injury; this proves that spikenard serves as an anti-inflammatory agent.

3. Relaxes the Mind and Body

Spikenard is a relaxing and soothing oil for the skin and mind; it’s used as a sedative and calming agent. It’s also a natural coolant, so it rids the mind of anger and aggression. It sedates feelings of depression and restlessness, and can serve as a natural way to bust stress.

A study done at the School of Pharmaceutical Science in Japan examined spikenard for its sedative activity using a spontaneous vapor administration system. The results indicated that spikenard contained a lot of calarene and its vapor inhalation had a sedative effect on mice. The study also indicated that when essential oils were mixed together, the sedative response was more significant; this was especially true when spikenard was mixed with galangal, patchouli, borneol and sandalwood essential oils.

The school also isolated two components of spikenard, valerena-4,7(11)-diene and beta-maaliene, and both compounds reduced the locomotor activity of mice. Valerena-4,7(11)-diene had a particularly profound effect, with the strongest sedative activity; in fact, caffeine-treated mice that showed locomotor activity that was double that of controls were calmed to normal levels by the administration of valerena-4,7(11)-diene. The mice slept 2.7 times longer, an effect similar to that of chlorpromazine, a prescription drug given to patients with mental or behavior disorders.

4. Stimulates the Immune System

Spikenard is an immune system booster; it calms the body and allows it to function properly. Spikenard is a natural hypotensive, so it naturally lowers blood pressure. Elevated blood pressure is when the pressure on the arteries and blood vessels becomes too high and the arterial wall becomes distorted, causing extra stress on the heart. Long term-high blood pressure increases the risk of stroke, heart attack and diabetes.

Using spikenard is a natural remedy for high blood pressure because it dilates the arteries, acts as an antioxidant to reduce oxidative stress and decreases emotional stress. Spikenard also relieves inflammation, which is the culprit for a host of diseases and illnesses.

A 2012 study conducted in India found that spikenard rhizomes (the stems of the plant) exhibited high reduction capability and powerful free radical scavenging. Free radicals are very dangerous to the body’s tissues and have been connected to cancer and premature aging; the body uses antioxidants to prevent itself from the damage caused by oxygen. Like all high antioxidant foods and plants, they protect our bodies from inflammation and fight free radical damage, keeping our systems and organs running properly.

5. Promotes Hair Growth

Spikenard oil is known for promoting the growth of hair, retaining its natural color and slowing down the process of graying. A 2011 study published in Pharmacognosy Magazine measured spikenard oil’s ability to stimulate hair growth. For the study, the crude extract, fractions and two of the isolated compounds were tested for their hair growth activity. Hair growth was tested on female Wistar rats that had hair removed in a four-centimeter square area before the study began.

The results indicate that spikenard oil showed positive response in hair growth promotion activity; the crude spikenard extracts were more effective than the pure compounds. Because the isolated compounds were effective in different ways, when they were acting together in the extract, hair growth resumed within a short period of time. When using spikenard extract, there was a 30 percent reduction in the time it look for the hair to grow back on the tested rats — showing that spikenard can work as a hair loss remedy.

6. Relieves Insomnia

Many adults experience insomnia at some point, but some people have long-term (chronic) insomnia. Insomnia may be the primary problem, or it may be secondary due to other causes, such as stress and anxiety, overuse of stimulants, sugar, indigestion, pain, alcohol, lack of physical activity, restless leg syndrome, hormonal changes, sleep apnea, or other medical conditions.

So if you can’t sleep, spikenard is a great natural remedy, without the use of drugs that can lead to other health issues. Spikenard’s sedative and laxative properties can be helpful for people with insomnia. It leaves you relaxed, and feelings of restlessness and anxiety fade away. If your insomnia is a result of indigestion or stomach issues, spikenard will prove helpful because it improves the working of the digestive system.

7. Relieves Constipation

Because it’s a natural laxative, spikenard stimulates the digestive system and keeps you running regularly. Unlike synthetic laxatives that dry out the intestinal wall, spikenard naturally keeps your poop moving through the colon and out of your body in the form of stool. Spikenard helps naturally relieve constipation, which is accompanied by a variety of symptoms such as bloating, gas, back pain or fatigue.

8. Protects Uterus and Ovaries

Spikenard purifies the uterus and ovaries and stimulates the secretion of estrogen and progesterone. This helps maintain the reproductive abilities of these vital organs. It’s been used in traditional and Ayurvedic medicine as a uterus stimulant for promoting menstruation, cleansing the uterus, treating painful menstruation and reducing inflammation of the uterus.

It can keep your menstrual cycle regular, and it serves as a natural remedy for PMS cramps and uncomfortable bloating. It was also used as an aphrodisiac in naturally treating impotence.


Spikenard History & Interesting Facts

The rhizomes and roots of the spikenard plant are used as antistress agents in traditional medicine, and spikenard is marketed in India as an anticonvulsant Ayurvedic drug. Spikenard is mentioned twice in the Bible, and the word nard in Hebrew means “light.” John 12:3 states: “Then took Mary a pound of ointment of spikenard, very costly, and anointed the feet of Jesus, and wiped his feet with her hair: and the house was filled with the odor of the ointment.”

Spikenard use dates back to ancient times when the Egyptians viewed it as a luxury and the Romans used it as perfume. Nard was also referenced in Homer’s Iliad when it was used to perfume the body of Patroklos by Achilles.

Grapeseed Oil Extract for Hair Loss – Can It Work?

Grapes, seeds and oil on a table

In this article you’ll learn exactly how to use grapeseed oil for hair loss in the most effective way possible. Back in 1998 Japanese researchers showed that grapeseed did have a positive affect on hair loss when tested on mice.

However, I want to show you how you can start using it today in your diet, and in a homemade shampoo recipe to immediately start seeing the benefits.

But before I get to that it’s important to understand the background benefits of grapeseed extract. And remember, this is just one very small part of regrowing your hair.

Finally, take the 6 question quiz (after reading the article) and calculate your own score. The higher the score, the more likely that grapeseed extract and other natural methods will work successfully for you.

Onwards…

What Is Grapeseed Extract?

Grapes have been used for 6,000 years, both as a delicious edible treat and for the treatment of a number of medical conditions. But what is it about these sweet, round berry fruits that lends itself to medicinal use, and what provides them with their curative powers?

The answer, of course, is their abundance of vitamins, nutrients, and complexes which can be found within the skins and seeds.

Grapeseed extract is the product of crushed grape seeds, and it’s been a staple in the diets and medicine cabinets of cultures all around the world.

How Can Grapeseed Extract Be Used to Prevent Hair Loss?

Grapeseed extract has a number of general health benefits.

From its use in the treatment of edema to its ability to control sugar levels, there’s no doubt that grapeseed extract has a number of extraordinary benefits. But what about its use in the treatment of hair loss?

Well, there’s a number of ways in which supplementation with grapeseed extract can help individuals with male-pattern baldness, and the below ways are just a few.

Grapeseed Extract Increases Blood Flow

Blood flow is the most important factor when it comes to the health of your hair. When blood flow is restricted then the miniaturization of the hair follicles is sure to follow.

This means the follicles are no longer able to support strong and healthy hair growth. One way to reverse these effects, however, is to increase the blood flow to these follicles. This will allow them to receive the nutrients they require.

With grapeseed oil extract supplementation, you can not only increase blood flow to the scalp and nutrient delivery to the hair follicles, but you can also stimulate hair growth.

Grapeseed Extract Promotes Hair-Cycle-Converting Activities

You know that the miniaturization of hair follicles can make it difficult for hair to regrow, but what exactly leads to the miniaturization of hair follicles?

For individuals suffering from Androgenetic Alopecia (also known as male-pattern baldness), the sex hormone DHT leads to the miniaturization. As the follicles become smaller, the hair cycle shortens.

dht-hair-cycle

Grapeseed extract, however, has actually been proven to jumpstart the hair cycleand push the follicle from the telogen phase (the phase in which the most hair is lost) to the anagen phase (the phase in which active hair growth occurs).

Grapeseed Extract Is Full of Antioxidants

Antioxidants play an important role in the fight against hair thinning and hair loss. And, fortunately, grapeseed oil is one natural and easy-to-obtain source of these free radical fighting molecules.

Grapeseed Extract is Antibacterial

MRSA is a difficult-to-treat infection which is seen in humans.

Scientists have been researching treatment options for years, and in 2010, researchers found that grapeseed extract is actually an effective treatment for this debilitating, and sometimes fatal, bacterium.

If grapeseed extract is effective at treating MRSA, then surely it’s an effective treatment for a number of less deadly bacterium found throughout the human body and on the scalp.

For those with hair loss, one of the most important things you can do is to keep your scalp and hair follicles healthy and free of infection.

This will make treatment for hair loss more effective, and it will keep your hair follicles from irreparable damage.

What Does the Research Have to Say About Grapeseed Extract and Hair Loss?

While no research has been done to directly link the use of grapeseed extract to hair loss treatment in humans, a few studies have shown the numerous benefits that grapeseed extract contains and how it can help to minimize hair loss and encourage hair growth.

grapeseed-extract-results-hair-lossOne such study, performed in 1998 by Japanese researchers, has proven that grapeseed extract is successful at promoting hair cycle conversions.

The study consisted of three groups of mice. All mice in the study were of the same age (8 weeks at the start), and the three groups each received topical applications of either A) control, B) 1% Minoxidil, or C) 3% proanthocyanidins purified from grape seeds.

The age of the mice is actually vital to the results of this study, as scientists know exactly when each phase of the hair cycle occurs at different ages.

For example, from ages 5 weeks to 14 weeks, the dorsal hair of C3H mice is in the telogen phase.

This is known as the resting phase and is actually the hair cycle phase where hair loss is most common.

This study lasted for 19 days, and the results can be clearly seen to the left.

Group A, the control group, showed the smallest amount of hair growth (about 30 – 40%). Group B, the Minoxidil group, saw a hair coverage of about 90 – 100%. And, astonishingly, Group C, the group which received a topical application of 3% proanthocyanidins from grape seeds, saw hair coverage of about 80 – 90% of the shaven area.

What does this have to do with the hair cycle?

Considering that the mice were receiving applications from 8 weeks old to 10 weeks old, the researchers knew that, naturally, the mice’s dorsal hairs would be in the telogen (resting) phase.

The applications of 1% Minoxidil and 3% proanthocyanidins actually caused hair to grow much quicker than in the mice who received applications of the control.

This means that the follicles in groups B and C actively went from the telogen phase (resting) to the anagen phase (active).

Can Grapeseed Extract Promote Hair Growth in Men with Male-Pattern Baldness?

While no human studies have been done, the above research study does highlight the abilities of grapeseed extract to promote hair growth.

This means that grapeseed extract has a very promising future as a treatment for men with male-pattern baldness.

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